02 02 This product is used to prepare storage tubes for collecting and transporting various viruses and related samples at room temperature. 1. Inactivated type: Viruses and bacteria lose their infectivity after the effects of receptive factors, called inactivation (inactivation). Most viruses are more likely to be inactivated than bacteria. This also makes long-term preservation of viruses usually more difficult than bacteria. In fact, most viruses are resistant to cold and heat, and are unstable to heat. At 55—60℃, usually within a few minutes, the capsid protein of the virus denatures, causing the virus to lose its infectivity. This may be because the virus has lost its ability to adsorb and/or strip normal cells at this time. Viruses have the disadvantage that they are not easy to store and are susceptible to infection, but inactivated virus preservatives perfectly solve this disadvantage. The virus preservation solution (inactivated type) uses high-concentration guanidine salt to quickly inactivate and preserve respiratory pathogens, so that the sample loses infectivity. The main purpose of it is to lyze the nucleic acid and release the nucleic acid, so that the nucleic acid test is carried out through subsequent real-time fluorescence RT-PCR to determine whether the sample contains viral nucleic acids, that is, infected with the virus. The system contains a high-efficiency virus lytic solution, which inactivates the virus immediately after sampling, effectively preventing the risk of secondary infection. The product can be stored at room temperature for 12 months before sampling, and the sample can be stored at room temperature for one week after sampling. It contains a nucleic acid Rnase inhibitor, which protects the virus nucleic acid from being degraded to a greater extent, and greatly improves the nucleic acid extraction efficiency. 022. Non-inactivated: It does not contain lytic salt, but the preserved virus has better integrity and a higher detection rate. It can also be used in other studies in addition to nucleic acid testing. As a protein stabilizer, bovine serum albumin (BSA) can form a protective film on the protein shell of the virus, making it difficult to decompose and guarantee the integrity of the virus; the neutral environment constructed by Hanks buffer helps to increase the survival time and infection stability of the virus. Non-inactivated virus preservatives are usually used for the collection and transportation of clinical influenza, avian influenza (such as H7N9), hand, foot and mouth disease, measles and other viral specimens, as well as mycoplasma, ureaplasma, chlamydia, etc. From the above information, it can be seen that both types of virus preservation solutions have their own advantages and disadvantages. The main advantages of inactivated virus preservation solutions are convenience, speed, and safety, and the disadvantage is that the detection rate is low; the main advantage of the non-inactivated type is that the detection rate is high, and the disadvantage is that it has a certain risk of infection, and each testing institution can choose according to its own specific testing needs